What's on the bench.
Arboreto
Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
Arbor
Autonomously improve a real artifact (code, training recipe, agent harness, data pipeline, prompt) against an objective and an evaluator, using Hypothesis Tree Refinement (HTR) from the Arbor paper. Use this whenever someone wants to iteratively optimize something over many experiments without overfitting — e.g. "get my model's eval score up", "improve this agent/harness", "tune this pipeline", "beat the baseline on this benchmark", "run a search over approaches and keep the best", "do an MLE-bench / Kaggle-style optimization", or any long-horizon "make this artifact better and don't just memorize the dev set" task. Trigger it even when the user doesn't say "Arbor" or "hypothesis tree" but describes repeated experiment-and-evaluate loops, branching exploration of competing ideas, or worries about a dev/test gap. Runs Claude itself as the coordinator with subagent executors in isolated git worktrees; for the standalone `arbor` CLI tool see references/arbor-upstream.md.
Anndata
Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.
Aeon
This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
Adaptyv
How to use the Adaptyv Bio Foundry API and Python SDK for protein experiment design, submission, and results retrieval. Use this skill whenever the user mentions Adaptyv, Foundry API, protein binding assays, protein screening experiments, BLI/SPR assays, thermostability assays, or wants to submit protein sequences for experimental characterization. Also trigger when code imports `adaptyv`, `adaptyv_sdk`, or `FoundryClient`, or references `foundry-api-public.adaptyvbio.com`.
Thumbnail Creator
Generate article or newsletter thumbnail candidates using the Gemini API from inside Claude Code. Claude reads article copy, proposes composition concepts, writes image generation prompts incorporating brand specs, calls Gemini to generate the images, evaluates the results via computer vision, and returns ranked candidates with rationale. Use when asked to create thumbnails, generate cover images, or produce visual candidates for an article or newsletter.
Substack Notes Scraper
Scrapes a Substack Notes page and exports engagement data to a formatted .xlsx file. Use when asked to download, analyse, or export Substack Notes performance data including likes, comments, and restacks. Produces a formatted spreadsheet with conditional formatting, summary stats, and per-note engagement metrics.
Instagram Post Downloader
Downloads and saves Instagram posts as high-resolution files. Use when asked to download, save, or archive an Instagram post, reel thumbnail, or carousel. Fetches images from Instagram's CDN, saves them into a named folder, and stitches carousel slides into a single PDF. Supports batch downloading of multiple URLs at once.
Stakeholder Influence Mapper
Map stakeholders for a product decision and produce a tailored influence strategy with talking points. Use when asked to get alignment, build consensus, get buy-in from engineering or finance or legal, navigate organisational resistance, or plan stakeholder conversations for a major initiative. Produces a stakeholder map, recommended conversation sequence, and tailored talking points per stakeholder.
Executive Update
Transform detailed product updates into concise executive briefings. Use when asked to write an executive update, leadership update, product update for the exec team, or a C-suite product briefing. Produces a structured 250-word briefing with headline, key metrics, progress, risks, decisions needed, and next steps.
Competitor Signal Tracker
Analyse competitor moves and translate them into strategic implications for your product roadmap. Use when a competitor announces a new feature, pricing change, partnership, or strategic shift, or when producing a periodic competitive intelligence report. Produces a categorised signal analysis with reactive-vs-proactive assessment, threat ratings, specific roadmap implications, and recommended responses with owners.
Competitive Intelligence Monitor
Monitor competitor signals and surface strategic implications for your roadmap. Use when asked to monitor competitors, track the competitive landscape, produce a competitive briefing, or understand what has changed in the market this week or month. Produces a structured intelligence brief with high/medium/low priority signals, roadmap implications, and a strategic landscape summary.
Ambiguity Resolver
Structure vague opportunities and unclear briefs into actionable one-page problem statements. Use when asked to clarify a vague brief, frame an undefined problem, make sense of an unclear opportunity, or when the user says 'we need to figure out what to do about X' or 'I've been asked to look into Y'. Produces a structured problem brief with reframed questions, scoped boundaries, and a minimum viable research plan.
Viral Content Framework
Build a framework for creating shareable, high-reach social media content. Use when asked to plan viral content, develop a shareable content strategy, create a hook writing system, or build a repeatable process for content that gets shared. Produces a platform-specific viral content framework with hook formulas, content structures, shareability triggers, and a content testing system.
Social Media Audit
Audit an existing social media presence across all active platforms. Use when asked to review social media performance, analyse a brand's social presence, benchmark against competitors, or identify what's working and what isn't. Produces a scored audit with platform-by-platform analysis, content performance review, competitive benchmarking, and a prioritised action plan.
Sales Forecasting Model
Build a structured sales forecast framework for any business or team. Use when asked to build a sales forecast, create a revenue model, project pipeline, or build a bottom-up forecast. Produces a forecast methodology, pipeline model, scenario analysis, and assumption log.
Sales Battlecard
Create a competitive sales battlecard for any competitor. Use when asked to build a battlecard, competitive comparison, sales cheat sheet, or objection handling guide for a specific competitor. Produces a one-page battlecard with positioning, differentiators, objection responses, and landmines.
Proposal Writer
Write a structured sales proposal or commercial proposal for any deal. Use when asked to write a proposal, sales proposal, commercial proposal, statement of work, or quote document. Produces a complete proposal with problem statement, solution, investment, and next steps.
Discovery Call Prep
Prepare a structured discovery call plan for any prospect. Use when asked to prepare for a sales call, discovery call, prospect meeting, or first call with a potential customer. Produces a call brief with research, hypotheses, questions, and success criteria.
Account Plan
Build a structured account plan for any key customer or target account. Use when asked to create an account plan, key account strategy, strategic account review, or territory plan. Produces a complete account plan with relationship map, growth opportunities, risks, and 90-day action plan.
Pm Weekly Review
Structure a PM's weekly review and planning session. Use when doing a weekly PM review, writing a weekly update, preparing for Monday planning, or reviewing sprint health. Produces a shareable weekly update covering metrics movement, shipping progress, blockers, insights, and next week's top 3 priorities.
Research Protocol
Write a structured research protocol or study design document. Use when asked to write a research protocol, study protocol, research plan, methodology section, or research proposal. Produces a complete protocol with objectives, methodology, ethical considerations, and analysis plan.
Literature Review
Structure and write a literature review for any research topic. Use when asked to write a literature review, systematic review summary, narrative review, or research background section. Produces a structured review with thematic organisation, critical analysis, and gap identification.
Roadmap Presentation
Create structured roadmap presentations calibrated to any audience. Use when asked to build a product roadmap, present roadmap to leadership, create a roadmap slide, or communicate quarterly plans to execs, teams, or customers. Produces an audience-calibrated Now/Next/Later roadmap with strategic context, initiative tables, success metrics, and explicit deprioritisation rationale.